Healthy Literature
蔓越莓所含的高原花青素是預防復發性尿路感染的關鍵嗎？
Are High Proanthocyanidins Key to Cranberry Efficacy in the Prevention of Recurrent Urinary Tract Infection?
/ 文獻筆記 /
本研究是採蔓越莓果粉（原花青素含量0.56％）測試是否可以預防復發性泌尿道感染的復發，經由182名女性為復發性泌尿道感染的患者其測試發現，每天服用500mg蔓越莓果粉連續六個月後的患者其發作次數明顯少於服用安慰劑組的患者。結果為蔓越莓果粉（含果皮，種子，果肉）可以降低具復發性尿路感染史的女性患者其復發感染的風險。
Most research on American cranberry in the prevention of urinary tract infection (UTI) has used juices. The spectrum of components in juice is limited. This study tested whether whole cranberry fruit powder (proanthocyanidin content 0.56%) could prevent recurrent UTI in 182 women with two or more UTI episodes in the last year. Participants were randomized to a cranberry (n = 89) or a placebo group (n = 93) and received daily 500 mg of cranberry for 6 months. The number of UTI diagnoses was counted. The intent-to-treat analyses showed that in the cranberry group, the UTIs were significantly fewer [10.8% vs. 25.8%, p = 0.04, with an age-standardized 12-month UTI history (p = 0.01)]. The Kaplan-Meier survival curves showed that the cranberry group experienced a longer time to first UTI than the placebo group (p = 0.04). Biochemical parameters were normal, and there was no significant difference in urinary phenolics between the groups at baseline or on day180. The results show that cranberry fruit powder (peel, seeds, pulp) may reduce the risk of symptomatic UTI in women with a history of recurrent UTIs.—文獻摘要
Copyright © 2015 John Wiley & Sons, Ltd—文獻出處
PMID: 26268913 DOI: 10.1002/ptr.5427
